Authors: D.A. Barantsev, V.A. Sannikova, Yu.R. Giniyatullina, Mizinkina , I.V. Isakova

Title of the article: Complexes of salts Me(II) with nicotinamide and kordiamin

Year: 2019, Issue: 2, Pages: 13-18

Branch of knowledge: 05.17.01 Technology of inorganic substances

Index UDK: 54-386:[546. 16.28.47.48.49.562.732.742.] 547-327

DOI: 10.26730/1999-4125-2019-2-13-18

Abstract: The widespread use of complex compounds as drugs is one of the promising directions in the development of coordination chemistry. In this paper, the aim was to determine the conditions for the synthesis of new complex compounds of some d-metals with multifunctional biologically active substances that have groups containing donor nitrogen and oxygen atoms, due to which a bond with the metal complexing is formed. In the course of the analysis of various literature sources, which describe the ability of organic ligands to form complexes, nicotinamide and cordiamine, as well as some anions were chosen as the starting substances for the synthesis. By experiments the sequence was established for mixing the solutions of initial components at a certain concentration; the resulting mixture of solutions was used to obtain crystalline compounds after a long period of crystallization at room temperature. The gross formula of the compounds was established by methods of chemical analysis, which made it possible to determine the number of the ligand molecules included in the composition and availability of water molecules for certain compounds. Comparison of data of IR spectroscopic method of analysis of initial substances and obtained compounds, as well as reference sources confirms participation in the formation of organic ligand compounds of water molecules and some functional groups that make up the anion, and in some cases, a method of coordination.

Key words: mixed ligand complexes coordination compounds of d-metals nicotinamide cordiamine thiocyanate-anion tetra(thiocyanato)mercurate(II)-anion hexafluorosilicate-anion IR spectroscopic analysis

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